Identification of physicochemical selective pressure on protein encoding nucleotide sequences

Nucleotide Sequence of Gene Encoding Capsid Protein VPI of Foot-and-Mouth Disease Virus / Type O1 Iran

Identification and Expression Analysis of Two Arabidopsis LRR-Protein Encoding Genes Responsive to Some Abiotic Stresses

AbstractTwo Arabidopsis thaliana genes, psr9.2 and psr9.4 appearedto be highly similar to a phosphate-starved induced gene,psr9, isolated from Brassica nigra suspension cells.Sequence analysis classified the encoded polypeptides asmembers of leucine-rich repeat (LRR) proteins superfamily.The sequence of psr9 proteins comprise a unique N-terminalregion e...

Variational auto-encoding of protein sequences

Proteins are responsible for the most diverse set of functions in biology. The ability to extract information from protein sequences and to predict the effects of mutations is extremely valuable in many domains of biology and medicine. However the mapping between protein sequence and function is complex and poorly understood. Here we present an embedding of natural protein sequences using a Var...

The Encoding of Architecture in Protein Sequences

Simulation of biomembranes over length and time scales relevant to cellular biology is not currently feasible with Molecular Dynamics including full atomic detail. Barring an unforeseen revolution in the computer industry, this situation will not change for many decades. Recent progress in simplified simulation models makes it possible to study lipid bilayers and biological membranes over long ...

Data Mining for Identification of Forkhead Box O (FOXO3a) in Different Organisms Using Nucleotide and Tandem Repeat Sequences

 Background: Deregulation of FOXO3a gene which belongs to Forkhead box O (FOXO) transcription factors, can cause cancer (e.g. breast cancer). FOXO factors have important role in ubiquitination, acetylation, de-acetylation, protein-protein interactions and phosphorylation. Understanding the regulation and mechanisms of FOXO3a can lead to cancer treatment. The aim of this study recent association...